Now accepting early access signups

The 24-Hour CognitiveArchitecture.

Optimize your waking focus and your sleeping recovery with the Day & Night Protocol.

2.4x
Focus improvement
2x
Deep sleep duration
24hr
Complete optimization
NeuroShift Product

Science-Backed

Developed by Harvard & MIT Scientists

Harvard Medical School
MIT

The Day & Night Protocol was developed by a team of neuroscientists and clinicians from Harvard Medical School and MIT to create a complete 24-hour cognitive optimization system that delivers results without the risks.

Our approach is rooted in clinical research and functional neuroscience. The Day Protocol combines novel nicotinic receptor agonists with synergistic peptides to target focus, memory, and mental clarity. The Night Protocol optimizes sleep architecture for maximum recovery. Both are backed by EEG data, functional benchmarking, and rigorous safety protocols.

Clinical Research

Grounded in peer-reviewed neuroscience

EEG Validation

Brainwave analysis confirms effects

Functional Testing

Cognitive benchmarks verify performance

How It Works

Precision-engineered
for your brain.

The Day & Night Protocol utilizes precision-engineered formulas for total circadian optimization—enhanced focus during waking hours and optimized recovery during sleep.

01

Day Protocol: Enhanced Focus

Safely activates nicotinic receptors for enhanced focus and alertness, without cardiovascular effects. Engineered for 8 hours of flow state and high-fidelity memory recall.

Day Protocol: Enhanced Focus
02

Day Protocol: Memory Optimization

A blend of peptides designed to support synaptic plasticity and memory formation. Maintains 95% accuracy in working memory tests throughout the day.

Day Protocol: Memory Optimization
03

Night Protocol: Sleep Architecture

Optimizes REM density and deep-wave delta stages using proprietary peptides. Doubles deep sleep duration so 6 hours feels like 8, with rapid sleep onset.

Night Protocol: Sleep Architecture

Interactive Clinical Data

Evidence-Based Performance

Real data from cognitive assessments and sleep architecture analysis

Working Memory (N-Back Test)

Measures ability to hold and process complex information in real-time.

Attention Span (EEG Beta Wave Power 13-30Hz)

Beta waves correlate directly with alert, active thinking. Increased power indicates a 'Flow State' free from distraction.

Mental Agility (Psychomotor Vigilance Task)

Measures reaction speed to stimuli. Lower latency means faster processing and sharper reflexes.

Select Your Protocol

The 24-Hour Cognitive Architecture

Optimize your waking focus and your sleeping recovery with the Day & Night Protocol.

NeuroShift DAY
SOLD OUT

NeuroShift DAY

Focus on Command.

The original nicotinic-peptide complex. Engineered for 8 hours of flow state, zero context switching, and high-fidelity memory recall.

$59.9930 Day Supply

NeuroShift NIGHT
SOLD OUT

NeuroShift NIGHT

Sleep Less, Rest More.

A hyper-efficient sleep architect. Optimize REM density and deep-wave delta stages so 6 hours feels like 8. Wake up fully primed.

$59.9930 Day Supply

Our Mission

Why We Built This

The supplement industry is broken.

With over 80,000 products on the market and minimal oversight, consumers are left vulnerable to ineffective formulas, hidden risks, and empty promises.

As researchers and clinicians, we've seen firsthand how the tools people rely on for productivity—caffeine, energy drinks, even prescription stimulants—come with serious downsides.

Jitters & CrashesShort-lived energy followed by burnout
Cardiovascular StrainLong-term health consequences
Tolerance & AddictionDiminishing returns, increasing dependence

We knew there had to be a better way.

Nicotine has long been recognized for its powerful cognitive benefits—enhanced focus, improved memory, faster reaction times. But its addictive properties and cardiovascular effects make it unsuitable for daily use.

That's where the Day & Night Protocol comes in.

The Day & Night Protocol Approach

Total circadian optimization

We've created a complete 24-hour system. The Day Protocol isolates the cognitive benefits of nicotine through a novel nicotinic receptor agonist, combined with cutting-edge nootropic peptides. The Night Protocol optimizes sleep architecture using proprietary peptides and natural compounds.

The result is a dual-formula system designed for sustained mental performance during the day and optimized recovery at night—without the side effects.

The Day & Night Protocol isn't just another supplement.

It's a complete 24-hour cognitive architecture—built by scientists, for people who demand total optimization of their waking focus and sleeping recovery.

Benefits

Experience the
clear difference.

2.4x
focus duration

Laser-Sharp Focus

Lock in on complex tasks for hours without distraction. (Day Protocol)

47%
recall improvement

Enhanced Memory

Access information instantly when you need it most. (Day Protocol)

2x
deep sleep

Deep Recovery Sleep

Double your deep delta wave sleep for maximum restoration. (Night Protocol)

12min
sleep latency

Rapid Sleep Onset

Fall asleep faster and wake up fully primed. (Night Protocol)

Focused work environment
"The clarity is unreal. It's like someone turned up the resolution on my thoughts."
Marcus Chen
AI Researcher

Testimonials

Trusted by
high performers.

I've tried everything. The Day Protocol is the first thing that's given me clean, sustained focus without any downsides.

Alex M.
Software Engineer
Series A Startup

The Night Protocol changed everything. I'm sleeping 6 hours and waking up more refreshed than 8 hours used to feel.

Sarah K.
Medical Student
Johns Hopkins

Using both protocols together—focus during the day, recovery at night. It's a complete system.

David R.
Founder & CEO
Y Combinator W24

Quality

Uncompromising standards.

Clinically-Inspired Formula

Developed using principles from neuroscience research and clinical trials

EEG & Functional Testing

Validated through brainwave analysis and cognitive performance benchmarks

Pharmaceutical-Grade Manufacturing

Produced in FDA-registered, GMP-certified facilities

30-Day Guarantee

Full refund, no questions asked

FAQ

Questions?

The Day & Night Protocol is a complete 24-hour cognitive optimization system. NeuroShift DAY enhances focus, memory, and mental clarity during waking hours. NeuroShift NIGHT optimizes sleep architecture for maximum recovery. They're designed to work together for total circadian optimization.
You can use either product independently based on your needs. Many users start with the Day Protocol for enhanced focus, or the Night Protocol for better sleep. However, using both together provides the most comprehensive cognitive optimization throughout your entire 24-hour cycle.
The Day Protocol uses NS-189, a novel nicotinic receptor agonist that provides cognitive benefits without the addictive properties of nicotine. The Night Protocol uses peptides and natural compounds designed for sleep optimization. Both formulas prioritize safety, but we always recommend consulting with a healthcare provider before starting any new supplement.
For the Day Protocol, many users report noticeable improvements in focus within 30-60 minutes. For memory enhancement and long-term cognitive benefits, most experience optimal results after 2-4 weeks. For the Night Protocol, sleep improvements are typically noticeable within the first few nights, with optimal results after 1-2 weeks of consistent use.
Yes. The Day Protocol works independently but can be combined with moderate caffeine intake. We recommend starting with the Day Protocol alone to assess your response, then adjust as needed. Many users find they need less caffeine when using the Day Protocol.
Take the Night Protocol 30-60 minutes before your desired bedtime. It's designed to help you fall asleep faster and optimize your sleep architecture, so you wake up feeling more refreshed even with less total sleep time.
We offer a 30-day money-back guarantee on both products. If you're not completely satisfied, return the unused portion within 30 days for a full refund—no questions asked.

Ready to optimize
your 24-hour cycle?

Join the waitlist to be first in line for the Day & Night Protocol. Early access members receive an exclusive 20% discount.

Limited to first 10,000 members. No credit card required.